In Agile project management, when a resource is lost and new requirements are added to the backlog, the project manager should reevaluate the backlog priority with the product owner. This is because the velocity, or the amount of work the team can handle in a given iteration, has been impacted. The project manager and the product owner need to reassess the priorities in the backlog to ensure that the most valuable items are being worked on given the current capacity of the team12. References:
* Agile Project Management: What Is It and Why Does It Matter?1
* Agile Project Manager Roles and Responsibilities: A Career Guide2