Risk response options are the most important factor to determine as a result of a risk assessment, as they involve selecting the optimal strategy and actions to address the identified and assessed risks, and align them with the risk tolerance and appetite of the organization. Process ownership, risk appetite statement, and risk tolerance levels are not the most important factors, as they are more related to the governance, definition, or communication of the risk, respectively, rather than the response to the risk. References = CRISC Review Manual, 7th Edition, page 108.