In this scenario, the chief information security officer (CISO) should be most concerned with developing a security program that meets the global and regional requirements of the organization. This includes considering the different legal and regulatory requirements of each operating location, and designing a security program that meets all of these requirements. The CISO should also ensure effective communication with local regulatory bodies to ensure compliance and understanding of the security program. Additionally, the CISO should use industry best practices and defined security policies and standards to ensure the program meets all applicable requirements.