After you install a Cisco ISE node, all the default services provided by the Administration, Policy Service, and Monitoring personas run on it. This node is in a standalone state. You must log in to the Admin portal of the Cisco ISE node to configure it. You cannot edit the personas or services of a standalone Cisco ISE node. You can, however, edit the personas and services of the primary and secondary Cisco ISE nodes. You must first configure a primary ISE node and then register secondary ISE nodes to the primary ISE node. Reference: https://www.cisco.com/c/en/us/td/docs/security/ise/2- 2/admin_guide/b_ise_admin_guide_22/b_ise_admin_guide_22_chapter_010.html