To migrate a Cisco WSA virtual appliance from one physical host to another physical host by using VMware vMotion, both hosts must have access to the same defined network. This is because vMotion preserves the network identity and connections of the virtual machine, and requires that the source and destination hosts have compatible CPUs and shared storage1. The hosts do not need to run the same or different versions of Cisco AsyncOS, as long as they meet the minimum requirements for the virtual appliance2. The hosts do not need to use a different datastore than the virtual appliance, as vMotion can migrate virtual machines across datastores as well3. References: 1: VMware vMotion: Live Migration of Virtual Machines and Storage 2: Cisco Secure Web Appliance Virtual - Cisco 3: Migrating to Virtual SMA from Physical - Cisco Community