https://portal.nutanix.com/page/documents/details?targetId=Web-Console-Guide-Prism-v5_10:wc-protection-do

The command ncli pd deactivate_and__destroy_vms name=<protection_domain_name> is a critical operation in managing Nutanix environments, particularly in scenarios involving disaster recovery and replication.
* This command deactivates the protection domain and deletes all VMs associated with that protection domain from the source site (Site A in this case). This operation is generally part of a planned migration or failover process where the VMs are intended to be run from the remote site (Site B).
* After this operation, the protection domain at Site A is no longer active, meaning it has been effectively removed along with its associated VMs, thus clearing the way for Site B to take over operations without conflict from the original site.
References:This action and its implications are covered under Nutanix disaster recovery and high availability strategies, detailed in both the Nutanix Bible and official Nutanix NCS-Core training materials, which discuss the management of protection domains and replication processes.