1 - Download the hotfix from LIfecycle Services
2 - Install the hotfix in your Microsoft Azure DevOps application development environment in a Pending state
3 - Check in the entire hotfix as pending change and schedule and deploy it to the production environment
4 - Build the hotfix in the development environment and accept changes
Reference:
https://docs.microsoft.com/en-us/dynamics365/unified-operations/dev-itpro/migration-upgrade/install-metadata-hotfix-package