Explanation:
Box 1: SQL Server on Azure VMs
SQL Server on Azure Virtual Machines can take advantage of Automated Backup, which regularly creates backups of your database to blob storage. You can also manually use this technique.
Box 2: Active geo-replication
Geo-replication for services such as Azure SQL Database and Cosmos DB will create secondary replicas of your data across multiple regions. While both services will automatically replicate data within the same region, geo-replication protects you against a regional outage by enabling you to fail over to a secondary region.
Reference:
https://docs.microsoft.com/en-us/azure/azure-sql/virtual-machines/windows/sql-server-on-azure-vm-iaas-what-is
https://docs.microsoft.com/en-us/dotnet/architecture/cloud-native/infrastructure-resiliency-azure