Explanation

Box 1: Override
Override: Ignore origin-provided cache duration; use the provided cache duration instead. This will not override cache-control: no-cache.
Set if missing: Honor origin-provided cache-directive headers, if they exist; otherwise, use the provided cache duration.
Incorrect:
Bypass cache: Do not cache and ignore origin-provided cache-directive headers.
Box 2: 1 hour
All media content must expire from the cache after one hour.
Box 3: Cache every unique URL
Cache every unique URL: In this mode, each request with a unique URL, including the query string, is treated as a unique asset with its own cache. For example, the response from the origin server for a request for example.ashx?q=test1 is cached at the POP node and returned for subsequent caches with the same query string. A request for example.ashx?q=test2 is cached as a separate asset with its own time-to-live setting.
Reference:
https://docs.microsoft.com/en-us/azure/cdn/cdn-query-string