The most influential factor on an organization's response to a new industry regulation is the organization's risk appetite. This is because the risk appetite defines the level of risk that the organization is willing to accept in pursuit of its objectives, and it guides the decision-making process for managing risks. The risk appetite also determines the extent to which the organization needs to comply with the new regulation, and the resources and actions required to achieve compliance. The risk appetite should be aligned with the organization's strategy, culture, and values, and it should be communicated and monitored throughout the organization.