Comprehensive and Detailed Step-by-Step Explanation: An effective information security program aims to manage risks to acceptable levels while supporting business objectives. A). Risk is treated to an acceptable level: This is the BEST answer as it directly reflects the program's success in mitigating risks within the organization's tolerance levels. B). The number of security incidents reported by staff has increased: An increase in reported incidents might indicate improved awareness but does not necessarily reflect overall effectiveness. C). Key risk indicators (KRIs) are established: KRIs are important for monitoring risks but do not indicate whether risks are being effectively managed. D). Policies are reviewed and approved by senior management: While essential, this action alone does not demonstrate the program's effectiveness. Reference: CISM Job Practice Area 2 (Risk Management) highlights the importance of risk treatment and its alignment with organizational risk tolerance.