For HPE GreenLake for Block Storage systems, particularly when equipped with two enclosures or cages, and considering a high availability (HA) level for drives, the maximum set size value that can be manually set is 6+2. This configuration means there are six data drives and two parity drives, ensuring that the system can withstand the failure of two drives while still protecting the data. Reference: HPE GreenLake Block Storage HPE Storage Availability and Performance