The best option to safeguard PII during an incident is to ensure permissions are limited in the investigation team and encrypt the data. This is because limiting permissions reduces the risk of unauthorized access or leakage of sensitive data, and encryption protects the data from being read or modified by anyone who does not have the decryption key. Option A is not correct because closing the data may hinder the investigation process and prevent collaboration with other parties who may need access to the data. Option C is not correct because deleting data that is no longer needed may violate legal or regulatory requirements for data retention, and may also destroy potential evidence for the incident. Option D is not correct because opening permissions to the company may expose the data to more people than necessary, increasing the risk of compromise or misuse. Reference: CompTIA CySA+ Study Guide: Exam CS0-002, 2nd Edition : CompTIA CySA+ Certification Exam Objectives Version 4.0.pdf)